Cancer, Natural Products and Nanodrug Delivery Systems
نویسندگان
چکیده
منابع مشابه
Camptothecin-based nanodrug delivery systems
The drug camptothecin has a wide range of antitumor effects in cancers including gastric cancer, rectal and colon cancer, liver cancer, and lung cancer. Camptothecin-based drugs inhibit topoisomerase 1 (Topo 1), leading to destruction of DNA, and are currently being used as important chemotherapeutic agents in clinical antitumor treatment. However, the main obstacle associated with cancer thera...
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Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential factors for MDR includes enhanced drug detoxification, decreased drug uptake, increased intracellular nucleophiles levels, enhanced repair of drug induced DNA damage, overexpression of drug transporter such as P-glycoprotein...
متن کاملRevolutionary Impact of Nanodrug Delivery on Neuroscience
Brain research is the most expanding interdisciplinary research that is using the state of the art techniques to overcome limitations in order to conduct more accurate and effective experiments. Drug delivery to the target site in the central nervous system (CNS) is one of the most difficult steps in neuroscience researches and therapies. Taking advantage of the nanoscale structure of neural ce...
متن کاملNovel delivery system for natural products: Nano-curcumin formulations
Objective: Curcumin is extracted from Curcuma longa and regulates the intracellular signal pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis. Curcumin molecules have special intrinsic features that can target the intracellular enzymes, genome (DNA) and messengers (RNA). A wide range of studies have been conducted on the physicochemical traits and pharmaco...
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Inflammatory Bowel Disease (IBD) classified with Ulcerative Colitis (UC) and Crohn Dis‐ ease (CD) is an idiopathic, life-long, destructive chronic inflammatory disease in gastrointes‐ tinal tract [1] and probably multi-factorial disease caused by interplay of the external and internal environment. Little is known about the mechanism of pathogenesis of the disease but it has been reported that i...
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ژورنال
عنوان ژورنال: Progress In Microbes & Molecular Biology
سال: 2020
ISSN: 2637-1049
DOI: 10.36877/pmmb.a0000089